Understanding how anesthetics work in the brain with the Salipro® platform - congrats to Ryan Hibbs and collaborators for publishing Salipro-GABA receptor structures in Nature. The study reveals mechanisms of anesthetics and psychoactive drugs binding to GABA receptors, opening up new ways to design novel and improved compounds. Salipro® and cryoEM for Structure Based Drug Design.
J. J. Kim, et al., Shared structural mechanisms of general anaesthetics and benzodiazepines. Nature (2020).