Salipro® in Japan! Congratulations to the Takagi and Nureki labs on the 4.1 Å cryoEM structure of a MFS transporter - 56 transmembrane helices in a lipid Salipro® environment. Find out more in the recent publication:
Find out more in the recent publication of the Schmitt lab: “We conclude that the Salipro-system is a seminal approach not only for structural, but also for the functional characterisation of membrane proteins.”
Title: Functional Reconstitution of HlyB, a Type I Secretion ABC Transporter, in Saposin-A Nanoparticles - Kerstin Kanonenberg, Sander H. J. Smits & Lutz Schmitt - Sci Rep. 2019 Jun 10;9(1):8436. doi: 10.1038/s41598-019-44812-0.
Link to publication >click here<
Here, we present DirectMX™ (link) for the direct extraction of membrane proteins from crude cell membranes into Salipro® particles with native lipids. The method presents new opportunities for the analysis of membrane proteins and identification of novel drug targets.
Contact us directly if you are interested in this recent application note.